The Therapeutic Roles of TAZ biomarker [WWTR1] in Cancer
Mahsa Mohammadzadeh1, Mehrdad Hashemi1*, Babak Negahdari2, 3 , Fatemeh Ghaemimanesh2
1 Faculty of advanced sciences and technology, Department of Genetics, Islamic Azad University, Tehran Medical Sciences , Tehran, Iran
2 Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
3 Department of Medical Biotechnology, School of Advanced Science in Medicine, Tehran University of Medical Science, Tehran, Iran
Many studies show the role of TAZ biomarkers in multiple malignancies. This study has focused on the significance of TAZ biomarker (WWTR1) in diagnosis or development of multiple cancers such as lung cancer, ovarian cancer, colorectal cancer, and breast cancer.
The use of biomarkers is now a new way of detecting many diseases, such as cancer. This way, for instance, more than 90% of ovarian cancers are diagnosed in their early stage.
This research is included in the results of the related articl
Keywords : TAZ biomarker, epithelial cancers, breast cancer, colorectal cancer, lung cancer, Hippo signaling pathway, TAZ activity